ea0081ep625 | General Endocrinology | ECE2022
Murray Carol
, McIntyre Angela
, McKeever Connor
, White Rebecca
, McBrinn Rachel
, Light Victoria
, Brown Susan
, Robinson Aron
, Clark Graeme
, Bingham Tilly
Regulators are concerned about the potential for environmental chemicals such as agrochemicals and their metabolites to perturb hormone systems. This has led to recommendations for the testing of potential endocrine disrupting chemicals1. The Steroidogenesis H295R assay is an in vitro cell model used to investigate compound effects on steroid hormone biosynthesis, specifically 17β-estradiol (E2) and testosterone (T). The human H295R adreno-carcinoma ce...